BDBM50275806 7-(4-fluorophenyl)-5-methyl-N-(3,4,5-trimethoxyphenyl)imidazo[1,5-f][1,2,4]triazin-2-amine::CHEMBL471816

SMILES COc1cc(Nc2ncc3c(C)nc(-c4ccc(F)cc4)n3n2)cc(OC)c1OC

InChI Key InChIKey=IVWUBHFTLDRTBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275806   

TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275806(7-(4-fluorophenyl)-5-methyl-N-(3,4,5-trimethoxyphe...)
Affinity DataIC50: 80nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed