BDBM50275849 (R)-3-Amino-N-(1,1-dioxo-4-thiazol-2-yl-hexahydro-1lambda*6*-thiopyran-4-yl)-4-(2-fluoro-phenyl)-butyramide::CHEMBL469538

SMILES N[C@@H](CC(=O)NC1(CCS(=O)(=O)CC1)c1nccs1)Cc1ccccc1F

InChI Key InChIKey=VTONGDFNEYFZND-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50275849   

TargetDipeptidyl peptidase 4(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50275849((R)-3-Amino-N-(1,1-dioxo-4-thiazol-2-yl-hexahydro-...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human Caco-2 cells-derived DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50275849((R)-3-Amino-N-(1,1-dioxo-4-thiazol-2-yl-hexahydro-...)
Affinity DataIC50: 190nMAssay Description:Inhibition of DPP4 in human Caco2 cell extracts using Ala-Pro-AFC as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50275849((R)-3-Amino-N-(1,1-dioxo-4-thiazol-2-yl-hexahydro-...)
Affinity DataIC50: 8.52E+4nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50275849((R)-3-Amino-N-(1,1-dioxo-4-thiazol-2-yl-hexahydro-...)
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50275849((R)-3-Amino-N-(1,1-dioxo-4-thiazol-2-yl-hexahydro-...)
Affinity DataIC50: 3.76E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed