BDBM50276091 CHEMBL469724::N-((1S)-3-(4-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)piperidin-1-yl)-1-phenylbutyl)cyclobutanecarboxamide

SMILES CC(C)c1nnc(C)n1C1CCN(CC1)C(C)C[C@H](NC(=O)C1CCC1)c1ccccc1

InChI Key InChIKey=PISDDJAHCRTSLZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276091   

TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276091(N-((1S)-3-(4-(3-isopropyl-5-methyl-4H-1,2,4-triazo...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50276091(N-((1S)-3-(4-(3-isopropyl-5-methyl-4H-1,2,4-triazo...)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed