BDBM50276362 CHEMBL4172205

SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc4n(C)cc(CN(C)C)c4c3)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=NGYZAUXCJZESQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276362   

TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276362(CHEMBL4172205)
Affinity DataIC50: 65nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276362(CHEMBL4172205)
Affinity DataIC50: 809nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed