BDBM50276447 CHEMBL456019::N-((S)-3-((1R,3S,5S)-3-(N-ethyl-2-(4-methoxyphenyl)acetamido)-8-azabicyclo[3.2.1]octan-8-yl)-1-phenylpropyl)cyclobutanecarboxamide

SMILES CCN([C@@H]1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(=O)C1CCC1)c1ccccc1)C(=O)Cc1ccc(OC)cc1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276447   

TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276447(N-((S)-3-((1R,3S,5S)-3-(N-ethyl-2-(4-methoxyphenyl...)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50276447(N-((S)-3-((1R,3S,5S)-3-(N-ethyl-2-(4-methoxyphenyl...)
Affinity DataIC50: 248nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed