BDBM50276474 (2R,4aR,10aR)-4a-Ethyl-2-phenyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,7-diol::CHEMBL462100

SMILES CC[C@@]12CC[C@@](O)(C[C@H]1CCc1cc(O)ccc21)c1ccccc1

InChI Key InChIKey=QTOLHRDDANXQPI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50276474   

TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276474((2R,4aR,10aR)-4a-Ethyl-2-phenyl-1,2,3,4,4a,9,10,10...)
Affinity DataIC50: 5.00E+3nMAssay Description:Transrepression activity at glucocorticoid receptor in human SW1353 cells assessed as repression of IL-1-induced MMP-13 production after 24 hrs by EL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276474((2R,4aR,10aR)-4a-Ethyl-2-phenyl-1,2,3,4,4a,9,10,10...)
Affinity DataIC50: 21nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276474((2R,4aR,10aR)-4a-Ethyl-2-phenyl-1,2,3,4,4a,9,10,10...)
Affinity DataIC50: 21nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276474((2R,4aR,10aR)-4a-Ethyl-2-phenyl-1,2,3,4,4a,9,10,10...)
Affinity DataIC50: 5.00E+3nMAssay Description:Transrepression activity at GR in human SW1353 cells assessed as inhibition of IL1-stimulated MMP13 production after 24 hrs by whole cell ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed