BDBM50276747 CHEMBL443362::c[RGDf-(3R)-Carboxymorpholine]

SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6@H]-2-[#6]-[#8]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6@@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7]-[#6]-1=O

InChI Key InChIKey=WEDAJTAXQYNGFD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50276747   

TargetIntegrin alpha-V(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50276747(c[RGDf-(3R)-Carboxymorpholine] | CHEMBL443362)
Affinity DataIC50: 32.6nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-V(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50276747(c[RGDf-(3R)-Carboxymorpholine] | CHEMBL443362)
Affinity DataIC50: 21nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50276747(c[RGDf-(3R)-Carboxymorpholine] | CHEMBL443362)
Affinity DataIC50: 6.5nMAssay Description:Displacement of [125I] echistatin from alphaVbeta3 integrin isolated from human placenta after 3 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed