BDBM50276978 1-(4-benzylpiperidin-1-yl)-2-(5-hydroxy-1Hindol-3-yl)ethane-1,2-dione::CHEMBL458155

SMILES Oc1ccc2[nH]cc(C(=O)C(=O)N3CCC(Cc4ccccc4)CC3)c2c1

InChI Key InChIKey=LIBJAJAOUAVCKG-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50276978   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50276978(1-(4-benzylpiperidin-1-yl)-2-(5-hydroxy-1Hindol-3-...)
Affinity DataIC50: 2.66E+3nMAssay Description:Displacement of [3H]ifenprodil from NMDA NR2B receptor in Wistar rat cerebral cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50276978(1-(4-benzylpiperidin-1-yl)-2-(5-hydroxy-1Hindol-3-...)
Affinity DataIC50: 2.66E+3nMAssay Description:Displacement of [3H]ifenprodil from NMDA receptor GluN2B subunit in Wistar rat cerebral cortex after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50276978(1-(4-benzylpiperidin-1-yl)-2-(5-hydroxy-1Hindol-3-...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H](+)pentazocine from sigma 1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed