BDBM50276994 CHEMBL459794::N-tert-butyl-2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthio)hexanamide

SMILES CCCCC(Sc1nc2ccccc2c(=O)n1-c1ccccc1)C(=O)NC(C)(C)C

InChI Key InChIKey=LEQZPZLQSCHFOS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276994   

TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50276994(N-tert-butyl-2-(4-oxo-3-phenyl-3,4-dihydroquinazol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal 6-His tagged human Chk1 by HTRF assay in presence of 0.1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed