BDBM50277024 1-(2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthio)hexanoyl)piperidine-4-carboxamide::CHEMBL460003

SMILES CCCCC(Sc1nc2ccccc2c(=O)n1-c1ccccc1)C(=O)N1CCC(CC1)C(N)=O

InChI Key InChIKey=BBSWOAJSCKRJDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277024   

TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277024(1-(2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthi...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of C-terminal 6-His tagged human Chk1 by HTRF assay in presence of 0.1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277024(1-(2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthi...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of C-terminal 6-His tagged human Chk1 by HTRF assay in presence of 0.2 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed