BDBM50277096 3-(6-(2-amino-1-methyl-1H-benzo[d]imidazol-4-yloxy)-1-oxo-3,4-dihydroisoquinolin-2(1H)-yl)propanoic acid::CHEMBL464399

SMILES Cn1c(N)nc2c(Oc3ccc4C(=O)N(CCC(O)=O)CCc4c3)cccc12

InChI Key InChIKey=VREIRRHIFCOWDQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277096   

TargetIntegrin alpha-V(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50277096(3-(6-(2-amino-1-methyl-1H-benzo[d]imidazol-4-yloxy...)
Affinity DataIC50: 39nMAssay Description:Binding affinity to human integrin alphavbeta3 receptor by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-V(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50277096(3-(6-(2-amino-1-methyl-1H-benzo[d]imidazol-4-yloxy...)
Affinity DataIC50: 600nMAssay Description:Binding affinity to human integrin alphavbeta5 receptor by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-IIb(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50277096(3-(6-(2-amino-1-methyl-1H-benzo[d]imidazol-4-yloxy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human integrin alpha2beta3 receptor by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed