BDBM50277194 4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfonyl)morpholine::CHEMBL474897

SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nc(CC(C)(C)C)cs1

InChI Key InChIKey=RJAYJQVMQVZMSL-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50277194   

TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277194(4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfo...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277194(4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfo...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor in cell free systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277194(4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfo...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50277194(4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfo...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]CP 55940 from human CB1 receptor in cell free systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50277194(4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfo...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB1 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed