BDBM50277226 4-(2-methyl-5-(5-neopentyl-1H-1,2,4-triazol-3-yl)phenylsulfonyl)morpholine::CHEMBL473697

SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nnc(CC(C)(C)C)[nH]1

InChI Key InChIKey=MRBHADJNBIAZSC-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277226   

TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277226(4-(2-methyl-5-(5-neopentyl-1H-1,2,4-triazol-3-yl)p...)
Affinity DataEC50:  64nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277226(4-(2-methyl-5-(5-neopentyl-1H-1,2,4-triazol-3-yl)p...)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277226(4-(2-methyl-5-(5-neopentyl-1H-1,2,4-triazol-3-yl)p...)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB1 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed