BDBM50277520 CHEMBL4164608

SMILES COc1ccc(-c2c([nH]c(N)c2C(=O)c2cccc(Cl)c2)C(=O)c2ccccc2)c(OC)c1

InChI Key InChIKey=GUPMDRLRHDKQPX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277520   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50277520(CHEMBL4164608)
Affinity DataIC50: 5.82E+4nMAssay Description:Inhibition of recombinant human 15-LOX-1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2020
Entry Details Article
PubMed