BDBM50277524 CHEMBL4169225

SMILES Cc1ccc(-c2c([nH]c(N)c2C(=O)c2cccc(Cl)c2)C(=O)c2ccccc2)c(C)c1

InChI Key InChIKey=QTCPSBKVJCZXOH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277524   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50277524(CHEMBL4169225)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of recombinant human 15-LOX-1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2020
Entry Details Article
PubMed