BDBM50277536 3-Cyclopentyl-4'-(2-{[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino}-ethyl)-N-(methylsulfonyl)biphenyl-4-carboxamide Dihydrochloride::CHEMBL479727

SMILES CS(=O)(=O)NC(=O)c1ccc(cc1C1CCCC1)-c1ccc(CCNC[C@H](O)c2cccnc2)cc1

InChI Key InChIKey=BVILZNWGKAMWOI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277536   

TargetBeta-3 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277536(3-Cyclopentyl-4'-(2-{[(2R)-2-hydroxy-2-pyridin-3-y...)
Affinity DataEC50:  0.290nMAssay Description:Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277536(3-Cyclopentyl-4'-(2-{[(2R)-2-hydroxy-2-pyridin-3-y...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed