BDBM50277831 5-(6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-ylamino)-N-phenylthiophene-2-carboxamide::CHEMBL485337

SMILES COc1cc2c(Nc3ccc(s3)C(=O)Nc3ccccc3)ncnc2cc1OCCCN1CCOCC1

InChI Key InChIKey=RPSFIQJOUUTWRS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277831   

TargetAurora kinase A(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277831(5-(6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-y...)
Affinity DataIC50: 11nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277831(5-(6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-y...)
Affinity DataIC50: 57nMAssay Description:Inhibition of aurora B kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed