BDBM50277923 CHEMBL3948191

SMILES Clc1ccc(cc1)S(=O)(=O)Nc1cccc2cccnc12

InChI Key InChIKey=JZSQETNTOFPAGF-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277923   

TargetBeta-glucuronidase(Bovine)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50277923(CHEMBL3948191)
Affinity DataIC50: 3.34E+4nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2020
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
University Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50277923(CHEMBL3948191)
Affinity DataIC50: 20nMAssay Description:Inhibition of bacterial NDM-1 (unknown origin) using imipenem as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
University Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50277923(CHEMBL3948191)
Affinity DataKi:  5.90E+3nMAssay Description:Binding affinity to bacterial NDM-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed