BDBM50277955 (R)-3-((3'-chloro-4'-fluorobiphenyl-4-yl)methyl)-5-methyloxazolidin-2-one::CHEMBL483750

SMILES C[C@@H]1CN(Cc2ccc(cc2)-c2ccc(F)c(Cl)c2)C(=O)O1

InChI Key InChIKey=RNJMIJHYCDJJMZ-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277955   

TargetMetabotropic glutamate receptor 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50277955((R)-3-((3'-chloro-4'-fluorobiphenyl-4-yl)methyl)-5...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at mGluR2 expressed in HEK cells by FLIPR assay in presence of glutamateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50277955((R)-3-((3'-chloro-4'-fluorobiphenyl-4-yl)methyl)-5...)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed