BDBM50278273 CHEMBL4173338

SMILES ONC(=O)CCCCCCNC(=O)c1ccc(CNC2(CC2)c2ccccc2)cc1

InChI Key InChIKey=VCBHRMLUMWBNCG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50278273   

TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278273(CHEMBL4173338)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant LSD1 (157 to 852 amino acids) (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 substrate by amplex red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278273(CHEMBL4173338)
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of C-terminal His-tagged human HDAC5 (656-1122 residues) expressed in baculovirus expression system using Ac-peptide substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278273(CHEMBL4173338)
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibition of MAOA (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278273(CHEMBL4173338)
Affinity DataIC50: 8.71E+4nMAssay Description:Inhibition of MAOB (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278273(CHEMBL4173338)
Affinity DataIC50: 15nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged human HDAC1 expressed in baculovirus expression system using Ac-peptide substrate incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278273(CHEMBL4173338)
Affinity DataIC50: 23nMAssay Description:Inhibition of C-terminal His-tagged full length human HDAC2 expressed in baculovirus expression system using Ac-peptide substrate incubated for 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed