BDBM50278275 CHEMBL4162637

SMILES Nc1ccccc1NC(=O)c1ccc(CNC2CC2c2ccccc2)cc1

InChI Key InChIKey=LIYQACIRFGXYBN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50278275   

TargetHistone deacetylase 2(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278275(CHEMBL4162637)
Affinity DataIC50: 413nMAssay Description:Inhibition of C-terminal His-tagged full length human HDAC2 expressed in baculovirus expression system using Ac-peptide substrate incubated for 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278275(CHEMBL4162637)
Affinity DataIC50: 7.16E+3nMAssay Description:Inhibition of recombinant LSD1 (157 to 852 amino acids) (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 substrate by amplex red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278275(CHEMBL4162637)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of MAOA (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278275(CHEMBL4162637)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MAOB (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278275(CHEMBL4162637)
Affinity DataIC50: 218nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged human HDAC1 expressed in baculovirus expression system using Ac-peptide substrate incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed