BDBM50278367 CHEMBL4170455

SMILES CC(C)NC(=O)CC[C@H](NS(=O)(=O)c1ccc(cc1)[N+]([O-])=O)C(O)=O

InChI Key InChIKey=LRLQSCGBFVRVPC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50278367   

Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278367(CHEMBL4170455)
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of recombinant human MMP2 (Tyr110 to Asp452 residues) using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate after 1 hr measured at 1 min tim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278367(CHEMBL4170455)
Affinity DataIC50: 5.97E+3nMAssay Description:Inhibition of recombinant human MMP9 (Phe107 to Pro449 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278367(CHEMBL4170455)
Affinity DataIC50: 3.01E+5nMAssay Description:Inhibition of recombinant human MMP14 (Tyr112 to Arg298 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278367(CHEMBL4170455)
Affinity DataIC50: 4.93E+5nMAssay Description:Inhibition of recombinant human MMP12 (Phe99 to Leu271 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2020
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278367(CHEMBL4170455)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant human MMP8 (Phe99 to Gln269 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2020
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278367(CHEMBL4170455)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant human MMP1 (Phe100 to Gln268 residues) using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate after 1 hr measured at 1 min tim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2020
Entry Details Article
PubMed