BDBM50278930 2-(m-tolylethynyl)pyrimidine::CHEMBL496882

SMILES Cc1cccc(c1)C#Cc1ncccn1

InChI Key InChIKey=GHGMWMJKRGZKMW-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50278930   

TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50278930(2-(m-tolylethynyl)pyrimidine | CHEMBL496882)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50278930(2-(m-tolylethynyl)pyrimidine | CHEMBL496882)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50278930(2-(m-tolylethynyl)pyrimidine | CHEMBL496882)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at mGlu2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50278930(2-(m-tolylethynyl)pyrimidine | CHEMBL496882)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at mGlu3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50278930(2-(m-tolylethynyl)pyrimidine | CHEMBL496882)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at mGlu4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50278930(2-(m-tolylethynyl)pyrimidine | CHEMBL496882)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at mGlu7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50278930(2-(m-tolylethynyl)pyrimidine | CHEMBL496882)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at mGlu8 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed