BDBM50279017 CHEMBL500434::cis-4-[6-(5-Methyl-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-pyridazin-3-yl]-phenol Bis-p-toluenesulfonate

SMILES CN1C[C@H]2CN(C[C@H]2C1)c1ccc(nn1)-c1ccc(O)cc1

InChI Key InChIKey=RTCJLANCSBJYNN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279017   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50279017(cis-4-[6-(5-Methyl-hexahydro-pyrrolo[3,4-c]pyrrol-...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]A585539 from alpha7 nicotinic acetylcholine receptor in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50279017(cis-4-[6-(5-Methyl-hexahydro-pyrrolo[3,4-c]pyrrol-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed