BDBM50279126 2-[5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-methyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazole-4-thio::CHEMBL524634

SMILES CN1C(=NC(=S)C1(C)C)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=CYHSJMXZGJNACF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50279126   

TargetCannabinoid receptor 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50279126(2-[5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-m...)
Affinity DataIC50: 6.30nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50279126(2-[5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-m...)
Affinity DataIC50: 901nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50279126(2-[5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-m...)
Affinity DataEC50:  8.5nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in HEK293 cells assessed as inhibition of CP-55940-stimulated Eu-GTP bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed