BDBM50279268 (Z)-3-({4-[(2-Dimethylaminoethyl)-methanesulfonyl-amino]-phenylamino}-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic Acid Methyl Ester::CHEMBL498266

SMILES COC(=O)c1ccc2C(C(=Nc3ccc(cc3)N(CCN(C)C)S(C)(=O)=O)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=QCTUWJMAPLGTOR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50279268   

TargetVascular endothelial growth factor receptor 3(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279268((Z)-3-({4-[(2-Dimethylaminoethyl)-methanesulfonyl-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279268((Z)-3-({4-[(2-Dimethylaminoethyl)-methanesulfonyl-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279268((Z)-3-({4-[(2-Dimethylaminoethyl)-methanesulfonyl-...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human VEGFR2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279268((Z)-3-({4-[(2-Dimethylaminoethyl)-methanesulfonyl-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279268((Z)-3-({4-[(2-Dimethylaminoethyl)-methanesulfonyl-...)
Affinity DataIC50: 69nMAssay Description:Inhibition of human VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed