BDBM50279287 3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynyloxy)phenylsulfonamido)propanoic acid::CHEMBL463395::rac-2-(4-But-2-ynyloxy-benzenesulfonyl-amino)-3-(5-benzyloxy-1H-indol-3-yl)-propionic acid

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)NC(Cc1c[nH]c2ccc(OCc3ccccc3)cc12)C(O)=O

InChI Key InChIKey=OPSGGAROSGLASJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50279287   

Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50279287(3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynylox...)
Affinity DataIC50: 3.27E+3nMAssay Description:Inhibition of MMP2 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50279287(3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynylox...)
Affinity DataIC50: 4.44E+3nMAssay Description:Inhibition of MMP13 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50279287(3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynylox...)
Affinity DataIC50: 6.98E+3nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50279287(3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynylox...)
Affinity DataIC50: 6.98E+3nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50279287(3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynylox...)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of MMP14 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50279287(3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynylox...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MMP1 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed