BDBM50279367 (1R,5S)-3-Pentyl-1,2,3,4,5,6-hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one::CHEMBL519673

SMILES CCCCCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2

InChI Key InChIKey=YKPIVRMIFPFYRZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50279367   

LigandPNGBDBM50279367((1R,5S)-3-Pentyl-1,2,3,4,5,6-hexahydro-1,5-methano...)
Affinity DataKi:  43.5nMAssay Description:Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50279367((1R,5S)-3-Pentyl-1,2,3,4,5,6-hexahydro-1,5-methano...)
Affinity DataKi:  332nMAssay Description:Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50279367((1R,5S)-3-Pentyl-1,2,3,4,5,6-hexahydro-1,5-methano...)
Affinity DataKi:  3.97E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nicotinic acetylcholine receptor in rat brain cortex membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed