BDBM50279765 CHEMBL215405::{2-{4-[5-Carboxymethoxy-4-(5-cyclohexylmethoxy-2-methoxy-4-methyl-benzyl)-2-methoxy-benzyl]-5-cyclohexylmethoxy-2-methoxy-benzyl}-5-[4-(2-carboxymethoxy-5-methoxy-benzyl)-2-cyclohexylmethoxy-5-methoxy-benzyl]-4-methoxy-phenoxy}-acetic acid

SMILES COc1ccc(OCC(O)=O)c(Cc2cc(OCC3CCCCC3)c(Cc3cc(OCC(O)=O)c(Cc4cc(OCC5CCCCC5)c(Cc5cc(OCC(O)=O)c(Cc6cc(OCC7CCCCC7)c(C)cc6OC)cc5OC)cc4OC)cc3OC)cc2OC)c1

InChI Key InChIKey=PEBLIJQBRLIYCA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50279765   

TargetNeutrophil elastase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50279765({2-{4-[5-Carboxymethoxy-4-(5-cyclohexylmethoxy-2-m...)
Affinity DataKi:  20nMAssay Description:Inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50279765({2-{4-[5-Carboxymethoxy-4-(5-cyclohexylmethoxy-2-m...)
Affinity DataKi: >1.50E+4nMpH: 7.5Assay Description:Inhibition of thrombin at pH 7.5 in HEPES buffer containing 200 mM NaCl with substrate Bz-Phe-Val-Arg-pNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin G(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50279765({2-{4-[5-Carboxymethoxy-4-(5-cyclohexylmethoxy-2-m...)
Affinity DataKi: >1.50E+4nMpH: 7.5Assay Description:Inhibition of cathepsin G at pH 7.5 in HEPES buffer containing 200 mM NaCl with substrate Suc-Ala-Ala-Pro-Phe-pNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed