BDBM50280331 CHEMBL49192::[9-Oxo-8-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-8-aza-spiro[4.5]dec-(7E)-ylidene]-acetic acid ethyl ester

SMILES CCOC(=O)\C=C1/CC2(CCCC2)CC(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=OAAZBZKVGLHRJX-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280331   

TargetType-1 angiotensin II receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280331([9-Oxo-8-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethy...)
Affinity DataIC50: 540nMAssay Description:Ability to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50280331([9-Oxo-8-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethy...)
Affinity DataKd:  12.6nMAssay Description:In vitro binding affinity against Angiotensin II receptor in rabbit aorta ringsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article