BDBM50280333 CHEMBL49207::[4,4-Diethyl-6-oxo-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-piperidin-(2E)-ylidene]-acetic acid ethyl ester

SMILES CCOC(=O)\C=C1/CC(CC)(CC)CC(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=SMAVFAOGHDJNBS-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50280333   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50280333([4,4-Diethyl-6-oxo-1-[2'-(1H-tetrazol-5-yl)-biphen...)
Affinity DataKd:  7.90nMAssay Description:In vitro binding affinity against Angiotensin II receptor in rabbit aorta ringsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

TargetType-1 angiotensin II receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280333([4,4-Diethyl-6-oxo-1-[2'-(1H-tetrazol-5-yl)-biphen...)
Affinity DataIC50: 20nMAssay Description:Ability to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50280333([4,4-Diethyl-6-oxo-1-[2'-(1H-tetrazol-5-yl)-biphen...)
Affinity DataKd:  7.94nMAssay Description:In vitro binding affinity against Angiotensin II receptor in rabbit aorta ringsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article