BDBM50280466 CHEMBL152239::[(2R,3R)-2-(2,2-Diphenyl-ethyl)-1-aza-bicyclo[2.2.2]oct-3-yl]-(2-fluoro-benzyl)-amine

SMILES Fc1ccccc1CN[C@@H]1C2CCN(CC2)[C@@H]1C(c1ccccc1)c1ccccc1

InChI Key InChIKey=AWHGFLZRMMYOLB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280466   

TargetSubstance-P receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280466([(2R,3R)-2-(2,2-Diphenyl-ethyl)-1-aza-bicyclo[2.2....)
Affinity DataIC50: 37nMAssay Description:Binding affinity towards Tachykinin receptor 1 binding in guinea pig cerebral cortex membranes was determined using [3H]SP as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetSubstance-P receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280466([(2R,3R)-2-(2,2-Diphenyl-ethyl)-1-aza-bicyclo[2.2....)
Affinity DataIC50: 990nMAssay Description:Binding affinity towards Tachykinin receptor 1 in rat cerebral cortex membranes was determined by using 125 [I]-BHSP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article