BDBM50280571 CHEMBL4167406

SMILES COc1ccc2c(C[C@H](N)C(=O)NC3CCN(Cc4c[nH]c5ccc(Cl)cc45)CC3)c[nH]c2c1

InChI Key InChIKey=HIERWWWDUQGXQN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280571   

TargetSon of sevenless homolog 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280571(CHEMBL4167406)
Affinity DataEC50:  1.51E+4nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed