BDBM50281586 (R)-3-{[(R)-1-((R)-2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2-carbonyl]-amino}-N-((1R,2S)-1-{(1R,2S)-1-[(R)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL347948

SMILES CC[C@H](C)[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI Key InChIKey=DEJOFTGYMOOOMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281586   

TargetEndothelin-1 receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50281586((R)-3-{[(R)-1-((R)-2-Acetylamino-3-phenyl-propiony...)
Affinity DataIC50: 45nMAssay Description:Inhibition of [125I]ET1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281586((R)-3-{[(R)-1-((R)-2-Acetylamino-3-phenyl-propiony...)
Affinity DataIC50: 15nMAssay Description:The inhibitory constant was evaluated against Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article