BDBM50281630 C,C,C-Trifluoro-N-{4'-[(2-trifluoromethyl-5,6,7,8-tetrahydro-quinazolin-4-ylamino)-methyl]-biphenyl-2-yl}-methanesulfonamide::CHEMBL165572

SMILES FC(F)(F)c1nc2CCCCc2c(NCc2ccc(cc2)-c2ccccc2NS(=O)(=O)C(F)(F)F)n1

InChI Key InChIKey=FENHKXVPGQPENW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281630   

TargetType-2 angiotensin II receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50281630(C,C,C-Trifluoro-N-{4'-[(2-trifluoromethyl-5,6,7,8-...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at angiotensin 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50281630(C,C,C-Trifluoro-N-{4'-[(2-trifluoromethyl-5,6,7,8-...)
Affinity DataIC50: 100nMAssay Description:Competitive inhibition of Angiotensin II receptor binding of radiolabeled AII to rat adrenal glomerulosa tissue by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2018
Entry Details