BDBM50281693 CHEMBL558614::N-[1-(8-Aza-spiro[4.5]decane-8-carbonyl)-4-(4-methyl-piperazin-1-yl)-4-oxo-butyl]-3,5-dichloro-benzamide; hydrochloride

SMILES CN1CCN(CC1)C(=O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)N1CCC2(CCCC2)CC1

InChI Key InChIKey=OTXDRNYCWZPODA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50281693   

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281693(N-[1-(8-Aza-spiro[4.5]decane-8-carbonyl)-4-(4-meth...)
Affinity DataIC50: 6.60E+3nMAssay Description:Displacement of [125I](BH)-CCK-8 to Cholecystokinin type A receptor in rat pancreatic aciniMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandPNGBDBM50281693(N-[1-(8-Aza-spiro[4.5]decane-8-carbonyl)-4-(4-meth...)
Affinity DataIC50: 700nMAssay Description:The compound was tested for its activity to inhibit the specific binding of [3H](N-methyl-N-leucine)-CCK-8 to Cholecystokinin type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandPNGBDBM50281693(N-[1-(8-Aza-spiro[4.5]decane-8-carbonyl)-4-(4-meth...)
Affinity DataIC50: 1.21E+5nMAssay Description:Displacement of [3H](N-methyl-N-leucine)-CCK-8 to Cholecystokinin type B receptor of guinea pig brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281693(N-[1-(8-Aza-spiro[4.5]decane-8-carbonyl)-4-(4-meth...)
Affinity DataIC50: 6.60E+3nMAssay Description:Displacement of [125I](BH)-CCK-8 to Cholecystokinin type A receptor in rat pancreatic aciniMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article