BDBM50281707 1-(9H-beta-Carbolin-3-yl)-3-((R)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea::CHEMBL354802

SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cc3c(c[nH]2)nc2ccccc32)C1=O)c1ccccc1

InChI Key InChIKey=SUJSQBYCMPEUIG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281707   

LigandPNGBDBM50281707(1-(9H-beta-Carbolin-3-yl)-3-((R)-1-methyl-2-oxo-5-...)
Affinity DataIC50: 270nMAssay Description:Tested for its activity to inhibit the binding of [125I]CCK-33 to Cholecystokinin type B receptor in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281707(1-(9H-beta-Carbolin-3-yl)-3-((R)-1-methyl-2-oxo-5-...)
Affinity DataIC50: 89nMAssay Description:Tested for its activity to inhibit the binding of [125I]CCK-33 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50281707(1-(9H-beta-Carbolin-3-yl)-3-((R)-1-methyl-2-oxo-5-...)
Affinity DataIC50: 400nMAssay Description:Tested for its activity to inhibit the binding of [125I]gastrin to gastric glands (gastrin) in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article