BDBM50281718 CHEMBL424211::{3-[3-(4-Chloro-phenyl)-ureido]-2-oxo-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)CN1c2ccccc2CCC(NC(=O)Nc2ccc(Cl)cc2)C1=O

InChI Key InChIKey=FPYPWEQDASHKPV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281718   

LigandPNGBDBM50281718({3-[3-(4-Chloro-phenyl)-ureido]-2-oxo-2,3,4,5-tetr...)
Affinity DataIC50: 180nMAssay Description:Ability to inhibit the binding of [125I]CCK-8 to Cholecystokinin type B receptor in guinea pig cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281718({3-[3-(4-Chloro-phenyl)-ureido]-2-oxo-2,3,4,5-tetr...)
Affinity DataIC50: 350nMAssay Description:Ability to inhibit the binding of [125I]CCK-8 to Cholecystokinin type A receptor in rat pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50281718({3-[3-(4-Chloro-phenyl)-ureido]-2-oxo-2,3,4,5-tetr...)
Affinity DataIC50: 120nMAssay Description:Ability to inhibit the binding of [125I]-gastrin to gastric glands in guinea pig.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article