BDBM50281721 1-{1-[2-(4-Methyl-piperazin-1-yl)-2-oxo-ethyl]-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl}-3-m-tolyl-urea::CHEMBL169807

SMILES CN1CCN(CC1)C(=O)CN1c2ccccc2CCC(NC(=O)Nc2cccc(C)c2)C1=O

InChI Key InChIKey=GNQCXUUHBSCALX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281721   

LigandPNGBDBM50281721(1-{1-[2-(4-Methyl-piperazin-1-yl)-2-oxo-ethyl]-2-o...)
Affinity DataIC50: 610nMAssay Description:Ability to inhibit the binding of [125I]-gastrin to gastric glands in guinea pig.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281721(1-{1-[2-(4-Methyl-piperazin-1-yl)-2-oxo-ethyl]-2-o...)
Affinity DataIC50: 970nMAssay Description:Ability to inhibit the binding of [125I]CCK-8 to Cholecystokinin type A receptor in rat pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50281721(1-{1-[2-(4-Methyl-piperazin-1-yl)-2-oxo-ethyl]-2-o...)
Affinity DataIC50: 5.00E+3nMAssay Description:Ability to inhibit the binding of [125I]CCK-8 to Cholecystokinin type B receptor in guinea pig cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article