BDBM50281722 CHEMBL423278::{3-[3-(3-Methoxy-phenyl)-ureido]-2-oxo-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetic acid tert-butyl ester

SMILES COc1cccc(NC(=O)NC2CCc3ccccc3N(CC(=O)OC(C)(C)C)C2=O)c1

InChI Key InChIKey=ZZVYLCABWVCVEG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281722   

LigandPNGBDBM50281722({3-[3-(3-Methoxy-phenyl)-ureido]-2-oxo-2,3,4,5-tet...)
Affinity DataIC50: 270nMAssay Description:Ability to inhibit the binding of [125I]CCK-8 to Cholecystokinin type B receptor in guinea pig cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281722({3-[3-(3-Methoxy-phenyl)-ureido]-2-oxo-2,3,4,5-tet...)
Affinity DataIC50: 62nMAssay Description:Ability to inhibit the binding of [125I]CCK-8 to Cholecystokinin type A receptor in rat pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50281722({3-[3-(3-Methoxy-phenyl)-ureido]-2-oxo-2,3,4,5-tet...)
Affinity DataIC50: 26nMAssay Description:Ability to inhibit the binding of [125I]-gastrin to gastric glands in guinea pig.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article