BDBM50281724 1-{1-[2-(4-Methyl-piperazin-1-yl)-2-oxo-ethyl]-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl}-3-naphthalen-1-yl-urea::CHEMBL169794

SMILES CN1CCN(CC1)C(=O)CN1c2ccccc2CCC(NC(=O)Nc2cccc3ccccc23)C1=O

InChI Key InChIKey=NOWQBQBDJXCZIK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281724   

LigandPNGBDBM50281724(1-{1-[2-(4-Methyl-piperazin-1-yl)-2-oxo-ethyl]-2-o...)
Affinity DataIC50: 5.40E+3nMAssay Description:Ability to inhibit the binding of [125I]-gastrin to gastric glands in guinea pig.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281724(1-{1-[2-(4-Methyl-piperazin-1-yl)-2-oxo-ethyl]-2-o...)
Affinity DataIC50: 3.20E+4nMAssay Description:Ability to inhibit the binding of [125I]CCK-8 to Cholecystokinin type A receptor in rat pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50281724(1-{1-[2-(4-Methyl-piperazin-1-yl)-2-oxo-ethyl]-2-o...)
Affinity DataIC50: 5.40E+3nMAssay Description:Ability to inhibit the binding of [125I]-gastrin to gastric glands in guinea pig.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article