BDBM50281844 CHEMBL4161204

SMILES CN(C)[C@H](CNC(=O)C1CCN(CC1)C(N)=O)c1cccs1

InChI Key InChIKey=PFUWNWPSEZEGHK-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281844   

TargetMu-type opioid receptor(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50281844(CHEMBL4161204)
Affinity DataKi:  2.43E+3nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50281844(CHEMBL4161204)
Affinity DataKi:  2.69E+3nMAssay Description:Displacement of [3H]U69593 from KOR (unknown origin) expressed in membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50281844(CHEMBL4161204)
Affinity DataEC50:  1.23E+4nMAssay Description:Agonist activity at MOR (unknown origin) expressed in HEK293T assessed as intracellular cAMP accumulation after 15 mins by luciferase based GloSensor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2020
Entry Details Article
PubMed