BDBM50282176 CHEMBL4169871

SMILES Cc1ccc(Nc2nc(Nc3ccc(F)c(Cl)c3)nc(n2)N2CCN(CC2)c2cc(C)nc3ncnn23)cc1

InChI Key InChIKey=PZHDBHCJUXSDHS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50282176   

TargetAcetylcholinesterase(Electric eel)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50282176(CHEMBL4169871)
Affinity DataIC50: 859nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50282176(CHEMBL4169871)
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50282176(CHEMBL4169871)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of HFIP-pretreated amyloid beta (1 to 42 residues) (unknown origin) self aggregation after 24 hrs by ThT-based fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMed