BDBM50282183 CHEMBL4167322

SMILES FC(F)(F)c1cccc(Nc2nc(NC3CC3)nc(n2)N2CCNCC2)c1

InChI Key InChIKey=NCWADNOZGFPCTN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50282183   

TargetAcetylcholinesterase(Electric eel)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50282183(CHEMBL4167322)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50282183(CHEMBL4167322)
Affinity DataIC50: 3.65E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50282183(CHEMBL4167322)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of HFIP-pretreated amyloid beta (1 to 42 residues) (unknown origin) self aggregation after 24 hrs by ThT-based fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMed