BDBM50282360 2-Ethyl-6,8-dimethyl-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-imidazo[1,2-b]pyridazine::CHEMBL67919

SMILES CCc1nc2c(C)cc(C)nn2c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=OMOOGKDUWPGBMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282360   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282360(2-Ethyl-6,8-dimethyl-3-[2'-(2H-tetrazol-5-yl)-biph...)
Affinity DataIC50: 5.70nMAssay Description:In vitro binding affinity evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II receptor, type 1 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282360(2-Ethyl-6,8-dimethyl-3-[2'-(2H-tetrazol-5-yl)-biph...)
Affinity DataIC50: 10nMAssay Description:In vitro binding affinity at AT2 receptor determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from rat brain memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article