BDBM50282434 CHEMBL354535::{6-[4'-(2-Butyl-6-isopropyl-4-oxo-4H-quinazolin-3-ylmethyl)-biphenyl-2-sulfonylamino]-6-oxo-hexyl}-carbamic acid tert-butyl ester

SMILES CCCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CCCCCNC(=O)OC(C)(C)C)C(C)C

InChI Key InChIKey=SVSIYIWGZAPXIV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282434   

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282434({6-[4'-(2-Butyl-6-isopropyl-4-oxo-4H-quinazolin-3-...)
Affinity DataIC50: 620nMAssay Description:In vitro displacement of 125I-[Sar1, Ile8] from AT2 receptors in rat midbrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282434({6-[4'-(2-Butyl-6-isopropyl-4-oxo-4H-quinazolin-3-...)
Affinity DataIC50: 12nMAssay Description:In vitro displacement of 125I-[Sar1, Ile8] from AT1 receptors in rabbit aorta membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article