BDBM50282589 2-{(S)-2-[3-(4-Hydroxy-phenyl)-1-phosphono-propylamino]-4-methyl-pentanoylamino}-3-(S)-1H-indol-3-yl-propionic acid::CHEMBL282663

SMILES CC(C)C[C@H](NC(CCc1ccc(O)cc1)P(O)(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI Key InChIKey=VPYRQVBWFJEUQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282589   

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282589(2-{(S)-2-[3-(4-Hydroxy-phenyl)-1-phosphono-propyla...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50282589(2-{(S)-2-[3-(4-Hydroxy-phenyl)-1-phosphono-propyla...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article