BDBM50282689 4-Amino-5-chloro-2-methoxy-benzoic acid 1-methyl-piperidin-4-yl ester::CHEMBL34224

SMILES COc1cc(N)c(Cl)cc1C(=O)OC1CCN(C)CC1

InChI Key InChIKey=FXYDPARKRWHKDN-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50282689   

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50282689(4-Amino-5-chloro-2-methoxy-benzoic acid 1-methyl-p...)
Affinity DataEC50:  110nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity as increased response to electrical stimulation in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50282689(4-Amino-5-chloro-2-methoxy-benzoic acid 1-methyl-p...)
Affinity DataIC50: 60nMAssay Description:5-hydroxytryptamine 4 receptor antagonist activity expressed as the concentration which produced a 50% reduction of 5-HT induced contraction in guine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282689(4-Amino-5-chloro-2-methoxy-benzoic acid 1-methyl-p...)
Affinity DataKi:  23nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50282689(4-Amino-5-chloro-2-methoxy-benzoic acid 1-methyl-p...)
Affinity DataKi:  72nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article