BDBM50282702 CHEMBL290768::Thiophene-2-carboxylic acid benzyl-{2-isopropyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,4-dihydro-quinazolin-6-yl}-amide

SMILES CC(C)c1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)N(Cc1ccccc1)C(=O)c1cccs1

InChI Key InChIKey=BJEGHUOJTHEZOS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50282702   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282702(Thiophene-2-carboxylic acid benzyl-{2-isopropyl-4-...)
Affinity DataIC50: 42nMAssay Description:Displacement of [125 I]Sar1Ile8-AII from type 1 Angiotensin II receptor of rabbit aorta membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282702(Thiophene-2-carboxylic acid benzyl-{2-isopropyl-4-...)
Affinity DataIC50: 0.240nMAssay Description:Displacement of [125 I]Sar1Ile8-AII from AT2 receptor of rat midbrain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensinogen(Rat)
Mnr College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50282702(Thiophene-2-carboxylic acid benzyl-{2-isopropyl-4-...)
Affinity DataIC50: 0.220nMAssay Description:Binding affinity to AT2 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed