BDBM50283044 CHEMBL4167570

SMILES O=C(Nc1ccc(cc1)-c1ccc2c(c1)[nH]cnc2=O)C1(CCC1)C(=O)Nc1cccc(c1)C#C

InChI Key InChIKey=AEGQTTCICHMYAC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50283044   

TargetVascular endothelial growth factor receptor 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283044(CHEMBL4167570)
Affinity DataIC50: 500nMAssay Description:Inhibition of VEGFR2 (unknown origin) using Poly E4Y1 substrate after 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283044(CHEMBL4167570)
Affinity DataIC50: 500nMAssay Description:Inhibition of EPHB4 (unknown origin) after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283044(CHEMBL4167570)
Affinity DataIC50: 22nMAssay Description:Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed